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For All My Startup Founders Workin’ it Out on a Sunday…

November 30th, 2009 by admin

Listening to this on the Blip.FM ContagionHealth channel while working on getupandmove.me UserVoice stuff.

Bang bang bang bang, vamanos, vamanos…

Posted via web from Jen’s Posterous

Nature Reviews Gastroenterology & Hepatology – Table of Contents alert Volume 6 Issue 12

November 30th, 2009 by admin

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY

December 2009 Volume 6 Number 12

Visit Nature Reviews Gastroenterology & Hepatology online to browse the
journal.

Now available at
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———————-
EDITORIAL
———————-
Indecent exposures
Stephen B. Hanauer
p685 | doi:10.1038/nrgastro.2009.204
http://links.ealert.nature.com/ctt?kn=48&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

———————-
RESEARCH HIGHLIGHTS
———————-
Pediatrics: Amitriptyline and placebo in children with functional
gastrointestinal disorders
p687 | doi:10.1038/nrgastro.2009.190
http://links.ealert.nature.com/ctt?kn=47&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Colonoscopy: Unsedated colonoscopy is a feasible primary screening tool for
colorectal cancer
p688 | doi:10.1038/nrgastro.2009.188
http://links.ealert.nature.com/ctt?kn=55&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Cancer: Human bacterium induces colon tumors in mice through activation of
TH17 cells
p688 | doi:10.1038/nrgastro.2009.189
http://links.ealert.nature.com/ctt?kn=54&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Targeting Ras in HCC
p689 | doi:10.1038/nrgastro.2009.191
http://links.ealert.nature.com/ctt?kn=53&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

IBD: Sargramostim for corticosteroid-dependent Crohn's disease
p689 | doi:10.1038/nrgastro.2009.192
http://links.ealert.nature.com/ctt?kn=52&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Ulcerative proctitis: Potential therapeutic role for appendicectomy
p689 | doi:10.1038/nrgastro.2009.194
http://links.ealert.nature.com/ctt?kn=12&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Liver transplantation: Predicting infectious complications after OLT
p690 | doi:10.1038/nrgastro.2009.187
http://links.ealert.nature.com/ctt?kn=14&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Fecal incontinence: Efficacy of biofeedback
p690 | doi:10.1038/nrgastro.2009.193
http://links.ealert.nature.com/ctt?kn=13&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

———————-
NEWS AND VIEWS
———————-
Primary sclerosing cholangitis: The importance of treating stenoses and
infections
Jens J. W. Tischendorf and Ramin Schirin-Sokhan
p691 | doi:10.1038/nrgastro.2009.181
The treatment of primary sclerosing cholangitis is a major challenge.
Complications such as dominant bile duct stenoses and biliary infections
are associated with poor outcomes. Data from a new prospective study with
a follow-up of 20 years now show that dominant stenosis and fungal, but
not bacterial infections reduce survival free of liver transplantation.
http://links.ealert.nature.com/ctt?kn=8&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Gastrointestinal bleeding: Carvedilol-the best [beta]-blocker for
primary prophylaxis?
Emmanuel A. Tsochatzis, Christos K. Triantos and Andrew K. Burroughs
p692 | doi:10.1038/nrgastro.2009.198
Endoscopic band ligation (EBL) and nonselective [beta]-blockade are two
effective strategies in the primary prevention of variceal bleeding.
Meta-analyses have shown an advantage of EBL over propranolol with regard
to bleeding rates but not mortality. By contrast, a recent randomized,
controlled trial shows less bleeding associated with the use of carvedilol
compared with EBL.
http://links.ealert.nature.com/ctt?kn=7&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Chronic anal fissure: Surgical or reversible neurochemical sphincterotomy?
Giuseppe Brisinda and Serafino Vanella
p694 | doi:10.1038/nrgastro.2009.200
The management of chronic anal fissure has received renewed interest and
has been re-evaluated over the past 20 years. The use of botulinum toxin
seems to be a promising and safe approach, particularly in patients at
high risk for incontinence. A recent meta-analysis investigated the efficacy
of botulinum toxin injection compared with lateral internal sphincterotomy
for the management of this condition.
http://links.ealert.nature.com/ctt?kn=10&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

GERD: Is laparoscopic surgery cost-effective?
Alexander C. Ford
p695 | doi:10.1038/nrgastro.2009.196
A Markov model using data from a randomized, controlled trial has
demonstrated that laparoscopic fundoplication is a cost-effective
intervention for the management of chronic GERD. However, there are some
limitations of the model, discussed below, which suggest that the results
should be viewed cautiously until longer follow-up is reported.
http://links.ealert.nature.com/ctt?kn=9&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Hepatocellular adenoma: Should phenotypic classification direct management?
Turkan Terkivatan and Jan N. M. Ijzermans
p697 | doi:10.1038/nrgastro.2009.199
The Bordeaux group has made major progress in the genotyping and phenotyping
of hepatocellular adenomas. Their efforts have allowed the classification
of hepatocellular adenomas into subtypes, which enhances our understanding
of this benign liver lesion. The clinical relevance of their findings is
open to debate.
http://links.ealert.nature.com/ctt?kn=4&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

———————-
REVIEWS
———————-
Epidemiology of pancreatic cancer: an overview
Sara Raimondi, Patrick Maisonneuve and Albert B. Lowenfels
Published online: 06 October 2009
p699 | doi:10.1038/nrgastro.2009.177
Pancreatic cancer, although infrequent, has an extremely high mortality
rate. The epidemiologic features of this rare cancer are still poorly known.
In this Review Raimondi and colleagues discuss the environmental, lifestyle
and genetic factors that increase or decrease the probability of developing
pancreatic cancer and that may explain the different incidence rates observed
in distinct subpopulations.
Abstract: http://links.ealert.nature.com/ctt?kn=3&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=6&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Anastomoses of the lower gastrointestinal tract
Govind Nandakumar, Sharon L. Stein and Fabrizio Michelassi
Published online: 03 November 2009
p709 | doi:10.1038/nrgastro.2009.185
Intestinal anastomoses are frequently performed to remove tumors or diseased
tissue. They have clear benefits but they can also lead to serious
complications such as dehiscences and strictures. This Review discusses
the surgical techniques, healing factors and perioperative and postoperative
strategies to minimize complications when performing anastomoses of the lower
gastrointestinal tract.
Abstract: http://links.ealert.nature.com/ctt?kn=27&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=26&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Endoscopy for upper gastrointestinal bleeding: is routine second-look
necessary?
Kelvin K. F. Tsoi, Philip W. Y. Chiu and Joseph J. Y. Sung
p717 | doi:10.1038/nrgastro.2009.186
A repeat endoscopic evaluation of a bleeding lesion on subsequent follow-up
is commonly called second-look endoscopy. Tsoi and colleagues review the
findings from five randomized, controlled trials and consider whether
second-look endoscopy can be recommended as routine practice, and which
groups of patients might benefit most. The cost-effectiveness of second-look
endoscopy and the use of PPIs versus second-look endoscopy are also discussed.
Abstract: http://links.ealert.nature.com/ctt?kn=25&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=24&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

Stem cells in gastroenterology and hepatology
Michael Quante and Timothy C. Wang
Published online: 03 November 2009
p724 | doi:10.1038/nrgastro.2009.195
Stem cells are primitive, relatively unspecialized cells that can self-renew
and are multipotent. In this Review, Quante and Wang discuss potential
types of stem cells found within the gastrointestinal tract, the
susceptibility of these stem cells for malignant transformation, and their
potential for use in restoring tissue function to treat gastrointestinal
disorders.
Abstract: http://links.ealert.nature.com/ctt?kn=23&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=22&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

———————-
PERSPECTIVES
———————-
OPINION
CT and radiation-related cancer risk-time for a paradigm shift?
David A. Johnson, Paul R. Helft and Douglas K. Rex
p738 | doi:10.1038/nrgastro.2009.184
The use of CT has been increasing exponentially over the past decade.
Unfortunately, there is little cognizance among health-care providers
(or their patients) about the relative latent cancer risks associated with
repetitive exposure to ionizing radiation. Given the exposure of a relatively
high proportion of the population to these tests, it is incumbent on
health-care providers to have an improved understanding of these risks and
discuss them accordingly with their patients.
Abstract: http://links.ealert.nature.com/ctt?kn=21&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=19&m=34450818&r=MTc2OTYyOTQ2MwS2&b=2&j=NjE2NjgxNzUS1&mt=1&rt=0

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Mucosal Immunology
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Indexed by MEDLINE and all content is hosted on PubMed!

Editors: Brian Kelsall, MD, Paul Garside, PhD and Jo Viney, PhD

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Kidney International – Table of Contents alert Volume 76 Supplement 114s

November 30th, 2009 by admin

KIDNEY INTERNATIONAL

December 2009 Volume 76 Number S114, pp S1 – S42

International Society of Nephrology
===================================
Your contribution is essential:
Renew your ISN membership now!
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———————-

———————-
INTRODUCTION
———————-
Beyond phosphate binding: the effect of binder therapy on novel biomarkers may have clinical implications for the management of chronic kidney disease patients
Gary E Striker
http://links.ealert.nature.com/ctt?kn=9&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0

———————-
REVIEWS
———————-
Role of oxidants/inflammation in declining renal function in chronic kidney disease and normal aging
Helen Vlassara, Massimo Torreggiani, James B Post, Feng Zheng, Jaime Uribarri and Gary E Striker
Abstract: http://links.ealert.nature.com/ctt?kn=7&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0
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Uremic toxins originating from colonic microbial metabolism
Pieter Evenepoel, Bjorn K I Meijers, Bert R M Bammens and Kristin Verbeke
Abstract: http://links.ealert.nature.com/ctt?kn=44&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0
Article: http://links.ealert.nature.com/ctt?kn=42&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0

Endotoxin-binding affinity of sevelamer: a potential novel anti-inflammatory mechanism
Phyllis P Sun, Mary C Perianayagam and Bertrand L Jaber
Abstract: http://links.ealert.nature.com/ctt?kn=46&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0
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Sevelamer and the bone-vascular axis in chronic kidney disease: bone turnover, inflammation, and calcification regulation
Vincent M Brandenburg, Willi Jahnen-Dechent and Markus Ketteler
Abstract: http://links.ealert.nature.com/ctt?kn=36&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0
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Clinical relevance of FGF-23 in chronic kidney disease
Sarah Seiler, Gunnar H Heine and Danilo Fliser
Abstract: http://links.ealert.nature.com/ctt?kn=38&m=34450984&r=MTc2MzAwNDQzNwS2&b=2&j=NjE2Njk0MTQS1&mt=1&rt=0
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The Google Wave Algorithm

November 30th, 2009 by admin

Google Wave Most days, I sit here worrying my pretty little head with the question What is Google Wave good for? (to the tune of Edwin Starr’s earworm Wave, huh, yeah / What is it good for / Absolutely nothing / Say it again). But slowly, the light is beginning to dawn.

Wave is not for:

  • Large groups of people (such as conference audiences) – too noisy and cumbersome.
  • Individuals – the communication element is strong, so unless you have a split personality, you’re better off organizing your thoughts in a document rather than a wave.
  • Small groups working on single documents such as a manuscript or planning document. Google Docs or Etherpad works perfectly well with this without the complications of Wave.

So, in the words of the song, what is it good for? No, not that. Unless you’re going to use the attributes of Wave, which means robots, plugins and all the other stuff which is going to appear over the next couple of years, you’re better off using something else. It’s possible that at some stage Wave may become such a prevalent medium that it becomes the default for words (and multimedia) on screen, but we’re a long way away from that at present. The precise timing of events will depend on the community that you are working with, in exactly the same way that Twitter was adopted in successive, err, waves. And if you’re not working in a community, you don’t need Wave.

And one more thing. Even if Wave is what email would look like if it were invented today (it isn’t, this is just a one liner the developers were forced to come up with at short notice for PR purposes – the Google PR department must be one of the scariest places in history), disruptive technologies augment rather than replace preceding ones. (Television did not replace radio, radio did not replace books, etc.) So while we wait to find out what Wave is good for, lets bear that in mind. Paul Buchheit suggests the future of Wave is to be integrated into the other Google offerings, producing a realtime environment for GMail and Google Documents. And he’s been right before.

Related:

Patient Modesty: Volume 28

November 29th, 2009 by admin

We continue on with a discussion about physicians, nurses and others in the healthcare system ignoring some patients’ modesty concerns and the need for a gender selection option offered to patients who wish to have their say in who examines and treats them. ..Maurice.

Graphic: Photograph from the Faculty of Nursing Science, Assumption University of Thailand and modified by me with Picasa3. If this was a real man and not a manikin in the photograph, some visitors to these Patient Modesty threads would find such a gathering rather disturbing.

Patient Modesty: Volume 27

November 29th, 2009 by admin

Yes, throughout these threads on patient modesty, it does appear that often what is missing and what should be corrected is the lack of communication on this issue both on the part of the patient but also on the part of the various healthcare providers, clinics and hospitals. It may be that many of both parties display modesty in communication by not speaking out or asking out about modesty. Hopefully, this issue of modesty in communication can be eliminated on both sides and that the concerns of patients in physical modesty can be resolved.

Continue writing.. ..Maurice.

Graphic: A photograph taken by myself at a local clinic and modified with Picasa3.

NOTICE: AS OF TODAY NOVEMBER 28, 2009 “PATIENT MODESTY: VOLUME 27″ WILL BE CLOSED FOR FURTHER COMMENTS. YOU CAN CONTINUE POSTING COMMENTS ON VOLUME 28.

ScienceDirect Alert: Cell, Vol. 139, Iss. 5, 2009

November 28th, 2009 by admin

ScienceDirect
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New Volume/Issue is now available on ScienceDirect


CellCell

Volume 139, Issue 5,  Pages 831-1024 (25 November 2009)


  Leading Edge
  1. In This Issue
Pages 831, 833
 
  2. Cancer Biology Select
Pages 835, 837
 
  Analysis
  3. Researchers Find Their Nemo
Pages 843-846
Anthony King
 
  Commentary
  4. The President’s Scientist
Pages 847-850
Neal F. Lane, Kirstin R.W. Matthews
 
  Book Review
  5. Let’s Get Physical
Pages 852-853
Boris I. Shraiman
 
  Essay
  6. Lipid Droplets Finally Get a Little R-E-S-P-E-C-T
Pages 855-860
Robert V. Farese Jr., Tobias C. Walther
 
  Previews
  7. Pushing and Pulling: Microtubules Mediate Meiotic Pairing and Synapsis
Pages 861-863
Sue L. Jaspersen, R. Scott Hawley
 
  8. RNAi: Prokaryotes Get in on the Act
Pages 863-865
John van der Oost, Stan J.J. Brouns
 
  9. X Chromosome Inactivation: When Dosage Counts
Pages 865-867
Elphège P. Nora, Edith Heard
 
  10. An Acid-Sensing Channel Sows Fear and Panic
Pages 867-869
Stephen Maren
 
  Review
  11. Epithelial-Mesenchymal Transitions in Development and Disease
Pages 871-890
Jean Paul Thiery, Hervé Acloque, Ruby Y.J. Huang, M. Angela Nieto
 
  Articles
  12. Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
Pages 891-906
Kandice R. Levental, Hongmei Yu, Laura Kass, Johnathon N. Lakins, Mikala Egeblad, Janine T. Erler, Sheri F.T. Fong, Katalin Csiszar, Amato Giaccia, Wolfgang Weninger, Mitsuo Yamauchi, David L. Gasser, Valerie M. Weaver
 
  13. Cytoskeletal Forces Span the Nuclear Envelope to Coordinate Meiotic Chromosome Pairing and Synapsis
Pages 907-919
Aya Sato, Berith Isaac, Carolyn M. Phillips, Regina Rillo, Peter M. Carlton, David J. Wynne, Roshni A. Kasad, Abby F. Dernburg
 
  14. Meiotic Chromosome Homology Search Involves Modifications of the Nuclear Envelope Protein Matefin/SUN-1
Pages 920-933
Alexandra M. Penkner, Alexandra Fridkin, Jiradet Gloggnitzer, Antoine Baudrimont, Thomas Machacek, Alexander Woglar, Edina Csaszar, Pawel Pasierbek, Gustav Ammerer, Yosef Gruenbaum, Verena Jantsch
 
  15. TFB2 Is a Transient Component of the Catalytic Site of the Human Mitochondrial RNA Polymerase
Pages 934-944
Marina Sologub, Dmitry Litonin, Michael Anikin, Arkady Mustaev, Dmitry Temiakov
 
  16. RNA-Guided RNA Cleavage by a CRISPR RNA-Cas Protein Complex
Pages 945-956
Caryn R. Hale, Peng Zhao, Sara Olson, Michael O. Duff, Brenton R. Graveley, Lance Wells, Rebecca M. Terns, Michael P. Terns
 
  17. Rapid E2-E3 Assembly and Disassembly Enable Processive Ubiquitylation of Cullin-RING Ubiquitin Ligase Substrates
Pages 957-968
Gary Kleiger, Anjanabha Saha, Steven Lewis, Brian Kuhlman, Raymond J. Deshaies
 
  18. Neuronal Subtype Specification within a Lineage by Opposing Temporal Feed-Forward Loops
Pages 969-982
Magnus Baumgardt, Daniel Karlsson, Javier Terriente, Fernando J. Díaz-Benjumea, Stefan Thor
 
  19. Assembly of Endogenous oskar mRNA Particles for Motor-Dependent Transport in the Drosophila Oocyte
Pages 983-998
Alvar Trucco, Imre Gaspar, Anne Ephrussi
 
  20. RNF12 Is an X-Encoded Dose-Dependent Activator of X Chromosome Inactivation
Pages 999-1011
Iris Jonkers, Tahsin Stefan Barakat, Eskeatnaf Mulugeta Achame, Kim Monkhorst, Annegien Kenter, Eveline Rentmeester, Frank Grosveld, J. Anton Grootegoed, Joost Gribnau
 
  21. The Amygdala Is a Chemosensor that Detects Carbon Dioxide and Acidosis to Elicit Fear Behavior
Pages 1012-1021
Adam E. Ziemann, Jason E. Allen, Nader S. Dahdaleh, Iuliia I. Drebot, Matthew W. Coryell, Amanda M. Wunsch, Cynthia M. Lynch, Frank M. Faraci, Matthew A. Howard III, Michael J. Welsh, John A. Wemmie
 
  Errata
  22. Writing Memories with Light-Addressable Reinforcement Circuitry
Page 1022
Adam Claridge-Chang, Robert D. Roorda, Eleftheria Vrontou, Lucas Sjulson, Haiyan Li, Jay Hirsh, Gero Miesenböck
 
  23. Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types
Page 1022
Joseph P. Doyle, Joseph D. Dougherty, Myriam Heiman, Eric F. Schmidt, Tanya R. Stevens, Guojun Ma, Sujata Bupp, Prerana Shrestha, Rajiv D. Shah, Martin L. Doughty, Shiaoching Gong, Paul Greengard, Nathaniel Heintz
 
  SnapShot
  24. SnapShot: Lipid Droplets
Pages 1024-1024.e1
Natalie Krahmer, Yi Guo, Robert V. Farese Jr., Tobias C. Walther
 



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Contagion Health’s First Web App Launches! Get Up and MOVE it!

November 27th, 2009 by admin

I’ll admit it. I fell off the wagon.

As a former cross country runner, newly minted vegequarian (pescatarian) and health 2.0 type, I used to live a pretty healthy life, full of 1.5 hour workouts. 

Ahh, those beautiful runs along the Embarcadero, those 3.5 hour, 7 mile hikes around Flag Pond in Southern Maryland. Gone, all gone, as soon as I got semi-serious about starting Contagion Health. 

When you’re founding a health software company, ironically fitness is the last thing on your mind. 

About 3 weeks ago I pulled on a pair of jeans and realized something was amiss. Largely amiss. And I decided to do something about it. 

But with healthcare conference season in full swing, a gig helping the kick-ass team at Dealmaker Media for a bit, a fellowship with the Health Strategy Innovation Cell at Massey College, UToronto, it was ridiculously hard to block off 1.5 hours to work out. 

To fix this big and increasingly burgeoning Battle of the Bulge, I’d need to start small. REALLY small. 

5 minutes of jogging here, dancing to a song while making morning coffee there, walking instead of taking the BART for 15 minutes to get to Safeway. 

“Losing weight” wasn’t the answer; it was committing myself to the idea that small acts of fitness, healthier microchoices made minute by minute – the way I live the rest of this crazy startup life – might actually have the power to add up and help me get back into my favorite pair of jeans. 

So I started asking friends to help motivate me.

Turns out, lack of motivation is one of the biggest problems we all have. It’s contagious. And it helped me realize why obesity may be epidemic. 

Talking with @alexdmoore and @garrytan about starting companies, I realized we’re all wailing about the same problems – a lack of motivation and a lack of time. 

We’re talking about people who don’t sleep here, who take our laptops into the bathroom with us. 

Unfortunately, these symptoms aren’t limited to startup founders.

Many of you who have been active and healthy at various times in your lives probably *used* to exercise a lot more. 

I have an uncle who *used* to run marathons. And several others are military vets and talk semi-longingly about PT.

But we all agree – in today’s crazy world it’s hard to get a workout in edgewise.

So at SuperHappyDevHouse (hosted by Palantir Technologies – @palantirtech), I started thinking big about getting healthy by starting small.

If I just needed to move more during my daily routine (or lack thereof) when I could fit in acts of microfitness – a few jumping jacks here, a few crunches there – and I just needed someone I know to help me get up off my a&^ and get moving, I’d use…

Twitter! 

Yep. If the people I know who use Twitter would just challenge me a bit, just ask me to get up and move, I’d feel beholden to answer their call. 

I’d feel obligated to #getupandmove more. 

I feel a responsibility and tie to my community there, especially since I’ve met (and worked with, and laughed with) many of you IRL.

So I roped a super-smart developer I know into working with me to motivate healthier microchoices, a few minutes of movement at a time. 

It’s microfitness for microblogging.

We’re trying not to assume too much about what motivates people.

We don’t know which person or what time period or what challenge will motivate you to move, but your FRIENDS and family using Twitter and Facebook *will.* 

The Get Up and Move web app lets you challenge people to small acts of microfitness – but with a spin – challenges are issued via Twitter and they’re private by default, sent through Direct Message. If you want to up the ante, you can RT the challenges publicly. 

And, you have to barter your own movement to issue a challenge. 

You have to shake it too in order to get someone else to move. 

As my co-creator Andrey Petrov (@shazow) says “Sometimes an excuse is all you need…Happy to be that vessel for people.”

It’s the first app Andrey and I built together, and he coded it in like .002 seconds (ok, so really it was like a week). 

There will be many future feature goodies and changes coming up as we iterate rapidly.

As you challenge us and we challenge you we learn more about what feels good, and what doesn’t. 

And by the way, please feel free to challenge Andrey (@shazow) and I (@jensmccabe) personally to get up and move. You can bet I’ll be doing the same for you.

It’s amazing what the ability to check off a completed challenge and say I’ve done my part can do. 

Tonight after cleaning up the remnants of a great Thanksgiving meal, @oldbailey and I checked out my Get Up and Move challenges and then went for a long walk/jog along Route 243 in St. Mary’s County. 

It was a beautiful night with stars visible and fog hugging the fields low and tight. I sung a few Christmas carols and we both talked about startup life. 

For the first time, working out didn’t feel like a burden – it felt like doing a favor for a friend who asked. 

So, I invite you to get up and move with us. Let us know what you want, what you think, what works, what doesn’t. 

Getting started is simple:

1. Follow @contagionhealth on Twitter.
2. Visit www.getupandmove.me and issue your first challenge. 
3. Be prepared to move it!

Tomorrow is Black Friday, and while you’re spending hard earned bucks to buy gifts, consider challenging someone to walk for 15 minutes. 

Best Buy will be crowded, but you’ll be motivating someone else to get healthy, a few minutes at a time. 

Now excuse me, I’ve got to go dance to 2 songs for @jeffreybrick.

Happy, healthy holidays to all!

Jen S. McCabe
@jensmccabe

CEO/Founder: Contagion Health 

CoFounder: NextHealth (NL)

LinkedIn: Jen McCabe 
Skype: jenmccabe

iPhone: 301.904.5136 
Dutch Mobile:  +31655585351

jennifermccabegorman@yahoo.com

Posted via email from Jen’s Posterous

Contagion Health’s First Web App Launches! Get Up and MOVE it!

November 27th, 2009 by admin

I’ll admit it. I fell off the wagon.

As a former cross country runner, newly minted vegequarian (pescatarian) and health 2.0 type, I used to live a pretty healthy life, full of 1.5 hour workouts. 

Ahh, those beautiful runs along the Embarcadero, those 3.5 hour, 7 mile hikes around Flag Pond in Southern Maryland. Gone, all gone, as soon as I got semi-serious about starting Contagion Health. 

When you’re founding a health software company, ironically fitness is the last thing on your mind. 

About 3 weeks ago I pulled on a pair of jeans and realized something was amiss. Largely amiss. And I decided to do something about it. 

But with healthcare conference season in full swing, a gig helping the kick-ass team at Dealmaker Media for a bit, a fellowship with the Health Strategy Innovation Cell at Massey College, UToronto, it was ridiculously hard to block off 1.5 hours to work out. 

To fix this big and increasingly burgeoning Battle of the Bulge, I’d need to start small. REALLY small. 

5 minutes of jogging here, dancing to a song while making morning coffee there, walking instead of taking the BART for 15 minutes to get to Safeway. 

“Losing weight” wasn’t the answer; it was committing myself to the idea that small acts of fitness, healthier microchoices made minute by minute – the way I live the rest of this crazy startup life – might actually have the power to add up and help me get back into my favorite pair of jeans. 

So I started asking friends to help motivate me.

Turns out, lack of motivation is one of the biggest problems we all have. It’s contagious. And it helped me realize why obesity may be epidemic. 

Talking with @alexdmoore and @garrytan about starting companies, I realized we’re all wailing about the same problems – a lack of motivation and a lack of time. 

We’re talking about people who don’t sleep here, who take our laptops into the bathroom with us. 

Unfortunately, these symptoms aren’t limited to startup founders.

Many of you who have been active and healthy at various times in your lives probably *used* to exercise a lot more. 

I have an uncle who *used* to run marathons. And several others are military vets and talk semi-longingly about PT.

But we all agree – in today’s crazy world it’s hard to get a workout in edgewise.

So at SuperHappyDevHouse (hosted by Palantir Technologies – @palantirtech), I started thinking big about getting healthy by starting small.

If I just needed to move more during my daily routine (or lack thereof) when I could fit in acts of microfitness – a few jumping jacks here, a few crunches there – and I just needed someone I know to help me get up off my a&^ and get moving, I’d use…

Twitter! 

Yep. If the people I know who use Twitter would just challenge me a bit, just ask me to get up and move, I’d feel beholden to answer their call. 

I’d feel obligated to #getupandmove more. 

I feel a responsibility and tie to my community there, especially since I’ve met (and worked with, and laughed with) many of you IRL.

So I roped a super-smart developer I know into working with me to motivate healthier microchoices, a few minutes of movement at a time. 

It’s microfitness for microblogging.

We’re trying not to assume too much about what motivates people.

We don’t know which person or what time period or what challenge will motivate you to move, but your FRIENDS and family using Twitter and Facebook *will.* 

The Get Up and Move web app lets you challenge people to small acts of microfitness – but with a spin – challenges are issued via Twitter and they’re private by default, sent through Direct Message. If you want to up the ante, you can RT the challenges publicly. 

And, you have to barter your own movement to issue a challenge. 

You have to shake it too in order to get someone else to move. 

As my co-creator Andrey Petrov (@shazow) says “Sometimes an excuse is all you need…Happy to be that vessel for people.”

It’s the first app Andrey and I built together, and he coded it in like .002 seconds (ok, so really it was like a week). 

There will be many future feature goodies and changes coming up as we iterate rapidly.

As you challenge us and we challenge you we learn more about what feels good, and what doesn’t. 

And by the way, please feel free to challenge Andrey (@shazow) and I (@jensmccabe) personally to get up and move. You can bet I’ll be doing the same for you.

It’s amazing what the ability to check off a completed challenge and say I’ve done my part can do. 

Tonight after cleaning up the remnants of a great Thanksgiving meal, @oldbailey and I checked out my Get Up and Move challenges and then went for a long walk/jog along Route 243 in St. Mary’s County. 

It was a beautiful night with stars visible and fog hugging the fields low and tight. I sung a few Christmas carols and we both talked about startup life. 

For the first time, working out didn’t feel like a burden – it felt like doing a favor for a friend who asked. 

So, I invite you to get up and move with us. Let us know what you want, what you think, what works, what doesn’t. 

Getting started is simple:

1. Follow @contagionhealth on Twitter.
2. Visit www.getupandmove.me and issue your first challenge. 
3. Be prepared to move it!

Tomorrow is Black Friday, and while you’re spending hard earned bucks to buy gifts, consider challenging someone to walk for 15 minutes. 

Best Buy will be crowded, but you’ll be motivating someone else to get healthy, a few minutes at a time. 

Now excuse me, I’ve got to go dance to 2 songs for @jeffreybrick.

Happy, healthy holidays to all!

Jen S. McCabe
@jensmccabe

CEO/Founder: Contagion Health 

CoFounder: NextHealth (NL)

LinkedIn: Jen McCabe 
Skype: jenmccabe

iPhone: 301.904.5136 
Dutch Mobile:  +31655585351

jennifermccabegorman@yahoo.com

Posted via email from Jen’s Posterous

Black Friday Pipeline

November 27th, 2009 by admin

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